DNA Replication… animated!

October 11, 2011 at 7:36 am Leave a comment

Hi everyone, just wanted to share an awesome video I was introduced to in class (shoutout to Zev Bryant)

This was shown as a motivation for the single-molecule study done on the replication machinery of bacteriophage T7.

Lee et al, “DNA primase acts as a molecular brake in DNA replication,” Nature, 439, 621-624 (2006).

To summarize the study, single-molecule experiments were set up in a very elegant fashion demonstrating that the primase prevents leading-strand synthesis from outpacing the slower enzymatic steps on the lagging strand by transiently halting progression of the replication fork.


Entry filed under: Uncategorized. Tags: , , .

Playing around with posts on individual pages “10-fold symmetry???”

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google+ photo

You are commenting using your Google+ account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )


Connecting to %s

Trackback this post  |  Subscribe to the comments via RSS Feed

Enter your email address to follow this blog and receive notifications of new posts by email.

Join 2 other followers

%d bloggers like this: